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The Center for Open Science (COS) is a non-profit organization based in Charlottesville, Virginia, USA. Its mission is to increase the openness, integrity, and reproducibility of scientific research. It promotes these aims by coordinating and catalyzing communities and stakeholders to drive change in global culture and incentives that drive researchers’ behavior, the infrastructure that supports their research, and the business models that dominate scholarly communication. Through its Open Science Framework, COS is providing a toolbox to make the entire research process transparent, accessible, collaborative, and verifiable – from the initial ideas through to the final research findings. The Transparency and Openness Promotion (TOP) Guidelines, launched by COS in 2015 and signed by over 5,000 signatories, along with all of the major publishers, have initiated an overdue transformation in the publishing culture.The center is highly regarded by its more than 350,000 users, who work across the social and behavioral sciences, the life sciences, the natural sciences, and educational research. 

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